CAS No:71989-33-8
Formula:C22H25NO5
China Export:From 2018.11 to 2019.11, total export volume of Fmoc-O-tert-Butyl-L-serine from China was 76,865,630KG while total export value was $825,816,556. The biggest proportion of exporting volume in the last 12 months was 14.24% in 2019.05.
Chemical Fmoc-O-tert-Butyl-L-serine Description
white to light yellow crystal powde
Chemical Fmoc-O-tert-Butyl-L-serine Basic Attributes
CAS No：71989-33-8
Molecular Formula ：C22H25NO5
Molecular Mass ：383.44
Exact Mass ：383.173279
PSA ：84.9 A^2
LogP ：3.5
EINECS ：276-260-6
InChIKeys ：REITVGIIZHFVGU-IBGZPJMESA-N
H-bond Acceptor ：5
H-bond Donor ：2
SP3 ：0.36
RBN ：8
Chemical Fmoc-O-tert-Butyl-L-serine Characteristics
Density ：1.2±0.1 g/cm3
Melting Point ：130.5-135.5 °C(lit.)
Flash Point ：303.7±30.1 °C
Refractive Index ：1.575
Storage Condition ：2-8°C
Specific Rotation ：25 º (c=1,EtOAc 24 ºC)
Chemical Fmoc-O-tert-Butyl-L-serine Safety Information
HS Code ：2924299090
UN No. ：NONH for all modes of transport
WGK_Germany ：3
Risk Code ：36/37/38
Safety Instructions ：24/25-36/37/39-27-26
Dangerous Mark ：Xi
P Code ：P261, P264, P270, P271, P272, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P321, P322, P330, P333+P313, P363, P501
Hazard Statements ：H302
Chemical Fmoc-O-tert-Butyl-L-serine Product Usage
Used for peptide synthesis and as amino acid protection monomer.
Chemical Fmoc-O-tert-Butyl-L-serine Production Methods
Suspend O-tert-butyl-L-serine in dioxane solution and acylate with fluorenylmethyloxycarbonyl azide to obtain a crude product, which is extracted with ethyl acetate at a pH of 9-10. Refined by recrystallization.
Chemical Fmoc-O-tert-Butyl-L-serine Material and Products
Material ：
N-(9-Fluorenylmethoxycarbonyloxy)succinimide, Fmoc-L-Serine, H-SER(TBU)-OH, 1,4-Dioxane, Fluorene
