Even in the smallest inch, the possibility of failure lengthens.

Being a mother itself is a hard-earned stance that passes extremities of its own. Women to motherhood is that patience bridge that needs careful steps to rail across.

But if one or two steps go wrong, the entire dedication fades instantly. 

Be deaf to the suspicion spray of the anti-vaccination enthusiasts who gel their own theory relating miscarriage with covid-19 vaccination states one of the best IVF centre in Hyderabad, Crysta IVF. 

Most IVF centres and Fertility hospitals in Hyderabad panel the best IVF Doctors who have successfully treated infertility and also have sound knowledge about the causes of miscarriage.

It is routine in pregnancy to undergo a series of diagnoses to ensure optimum health of the fetus and the mother which is followed by the best infertility centre in Hyderabad. But all diagnoses aren’t comprehensive and might miss out on living its moral. 

What we ignore as minor may turn out to be a major cause of miscarriage.

There are several roots leading to miscarriage, but there are two conditions that are less talked about, and a handful of content floats digitally to provide a deeper insight.

Maternal Cell Contamination (MCC)- The Miss-Out

To define MCC – 

The sample mix of uterus cells with the fetal cells is MCC which results in false genetic evaluation during chromosome analysis. 

The opportunity is foregone in selecting the fetus sample for chromosome testing, and using uterus cell sample for chromosomal evaluation.

Out of many, chromosome analysis is one of the important tests that a woman in her pregnancy undergoes.  

The chromosomal diagnosis is to check the fetus for abnormal conditions. 

Karyotyping is a cytogenesis analysis that is performed to check for chromosomal ambiguities in the fetus using tissue sampling. But it has limitations in recognition, and mostly tends to produce false reports.

It fails to provide contrasting parameters to lay the distinction between uterus cell and fetus cell. This method is prone to overlook MCC. 

One of the risks associated with prenatal testing is maternal cell contamination (MCC), which happens when a fetal sample combines with maternal tissues or blood. 

Event of MCC happens is during –

  • Chorionic Villus Sampling, 
  • Amniocentesis, 
  • Extraction of Cord Blood 

It may happen sometime during chromosomal testing that instead of a fetus sample, the uterus sample is extracted unintentionally, or both are mixed and sent for diagnosis. This leads to Maternal Contamination.

The lab report so obtained dictates the chromosomal attributes of the mother. At this stage, it is nearly impossible to determine which sample hails from the uterus or fetus. 

Maternal Contamination causes miscarriage and is proven based on clinical trials and assessments. In cases of MCC, the value of Karyotype is limited which may compromise the results.

The probability of false genetic testing is high when there is the presence of MCC during fetal DNA testing.

To avoid MCC instances, the need is for the best IVF centre, fertility hospital like it is in Hyderabad at Crysta IVF.  In IVF fertility hospitals, methods are available to make out a clear distinction between a specimen of maternal blood and fetal attributes.

Retained Products of Conception – RPOC

It is insisted to have a uterus flush-clean after pregnancy, miscarriage as it may hurdle the next conception. The substances of miscarriage persist if the residuals of previous pregnancy or miscarriage exist in the uterus.

The remnants of previous pregnancy are known as Product of Conception (POC) or RPOC like –

  • Uterus scrapings
  • Fetal tissues
  • Retained Placenta bits
  • Residual trophoblastic tissue (TOP)

To establish closer relativity, products of conception is all about the intrauterine tissues that develop post-pregnancy or post-abortion/miscarriage during –

  • Post Medical Abortion
  • Surgical termination of pregnancy  
  • Miscarriage
  • Vaginal delivery
  • Cesarean delivery

Symptoms of miscarriage

If not through diagnosis, one can make out about the presence of RPOC by its symptoms, like –

  • Uterine bleeds
  • Pelvic pain
  • Fever, and/or
  • Tender Uterine

The best practice adopted by the best IVF centre in Hyderabad on diagnosing cases of RPOC is to flush-clear the uterus. It can also be removed after delivery, miscarriage preserving fertility.

But if left untreated, the remains of products of conception may lead to complications resulting in miscarriage or infertility.

This is the very reason why hysteroscopy emerged as a savior for patients with RPOC conditions as it shields the uterine cavity reducing the risk of intrauterine attach and preserves fertility.

The solution is always there, and are available at the right fertility hospital and in the best IVF centre in Hyderabad

With the right testing protocol in place, assessment Maternal Contamination and Products of Conceptions could be managed in an efficient manner.

It is already clinically proven that, based on the evaluation of visual POC material & MCC testing, results in authentic POC genetic testing.