Both of these conditions:
PANS – Pediatric Acute-onset Neuropsychiatric Syndrome
PANDAS – Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections
Are autoimmune encephalopathies that result in extreme illness and complications by attacking the basal ganglia of the brain.
These conditions are interlinked with each other. PANDAS is the title used when the signs and symptoms have a documented link with group A Streptococcus infections, whereas PANS is mainly a general term that is used to describe symptoms that can result from one or more infectious organisms or contagions. Both conditions arise from a misdirected immune reaction against certain target areas in the brain, which are triggered by pathogens or some other factors. This autoimmune response affects the neurological functioning negatively and triggers a usually prompt, severe onset of Obsessive-Compulsive Disorder (OCD), restricted food intake, anxiety, tics, and additional symptoms that can occur either quickly after the illness or several months following infection. PANS/PANDAS symptoms usually disappear and then reappear with flare-ups, symptoms can get worse, and new symptoms can occur, usually after exposure to any type of viral disease or even in the surroundings of someone else who is unwell. Anything that makes the inflammation worse in the brain or body can give rise to a flare!
How to balance the Immune Response, which becomes dysregulated in PANS
Most of the time, it is preferred to use a combination therapy of the following;

  • Low Dose Naltrexone: It is a compounded medicine that momentarily inhibits the body’s endogenous opioid receptors. It makes the body consider it is not producing enough endorphins. As a response, extra endorphins are then generated, which help with reduction in pain, balance the immune system (usually used to help autoimmune diseases, which is basically what PANS/PANDAS is), decreasing inflammation (it proves beneficial in autism and depression), and Low Dose Naltrexone can even help patients with some forms of cancer.
  • Serum Bovine Immunoglobulins: They strengthen the immune system in the digestive system (which is where the maximum of the immune system exists) as well as assist in fighting contaminations in the gut and heal it.
  • Use of a special herbal recipe that makes the immune system overreaction, to calm down.
  • Transfer Factors that increase the level of the Natural Killer Cells in the Immune System and also decrease the TH17 immune cells (which control the autoimmunity). Particular Transfer Factors also support in “programing” the immune system to combat specific bacteria and viruses.

Reference post link: https://harborcompounding.weebly.com/home/what-is-pans-and-how-is-it-treated