Bioglandin 500mcg Injection improves blood flow in such babies who have PDA. It is given as an injection by a doctor or nurse in a hospital setup Bioglandin Injection is used to treat patent ductus arteriosus (PDA), a heart defect that occurs in newborns.Do not use more than one dose of Bioglandin Injection in a 24-hour period or more than 3 doses per week without first checking with your doctor.