Overview
Glutathione is an antioxidant produced in cells. It’s comprised largely of three amino acids: glutamine, glycine, and cysteine.
Glutathione levels in the body may be reduced by a number of factors, including poor nutrition, environmental toxins, and stress. Its levels also decline with age.
In addition to being produced naturally by the body, glutathione can be given intravenously, topically, or as an inhalant. It’s also available as an oral supplement in capsule and liquid form. However, oral ingestion of glutathione may not be as effectiveTrusted Source as intravenous delivery for some conditions.
Glutathione benefits
- Glutathione Reduces oxidative stress
Oxidative stress occurs when there’s an imbalance between the production of free radicals and the body’s ability to fight them off. Too-high levels of oxidative stress may be a precursor to multiple diseases. These include diabetes, cancer, and rheumatoid arthritis. Glutathione helps stave off the impact of oxidative stress, which may, in turn, reduce disease.
An article cited in Journal of Cancer Science and Therapy indicated that Glutathione deficiency leads to increased levels of oxidative stress, which might lead to cancer. It also stated that elevated Glutathione levels raised antioxidant levels and resistance to oxidative stress in cancer cells.
- Glutathione May improve psoriasis
A small studyTrusted Source indicated that whey protein, when given orally, improved psoriasis with or without additional treatment. Whey protein had been previously demonstrated to increase glutathione levels. Study participants were given 20 grams as an oral supplement daily for three months. Researchers stated that more study is needed.
- Glutathione Reduces cell damage in alcoholic and nonalcoholic fatty liver disease
Cell death in the liver may be exacerbated by a deficiency in antioxidants, including glutathione. This can lead to fatty liver disease in both those who misuse alcohol and those who don’t. Glutathione has been shown to improve protein, enzyme, and bilirubin levels in the blood of individuals with alcoholic and nonalcoholic chronic fatty liver disease.
A studyTrusted Source reported that Glutathione was most effective when given to people with fatty liver disease intravenously, in high doses. Participants in the study also showed reductions in malondialdehyde, a marker of cell damage in the liver.
